Lyme Disease

Symptoms

painful-arms What are the Symptoms of Lyme disease?

Lyme Disease has been called the great imitator of our century.  Many people are initially misdiagnosed with Fibromyalgia, Chronic Fatigue Syndrome, Raynaud’s Syndrome, Multiple Sclerosis, Scleroderma, lupus, early Alzheimers, ALS, many types of arthritis, including but not limited to Rheumatoid, Osteo and Juvenile arthritis; Interstitial Cystitis, GERD, irritable bowel disease, Bell’s Palsy, Colitis, Fifth Disease, psychiatric disorders, seizures, Gulf war syndrome, ADHD, Parkinson’s Disease, and hypochondria. 

Lyme Disease has now been shown to affect every organ and organ system in the body, producing a variety of symptoms at different stages of the disease.  It is said by some Lyme specialists[1] that Lyme can cause any symptom and any disease like its close cousin Syphilis.  It has been shown that certain manifestations of Lyme can also take up to a decade or more to develop.[2] 

Lyme Disease is classified in stages:

 
 
 
 
Stage 1, called Early or Early Localized Lyme Disease, usually occurring within days or weeks of the initial tick bite.   Typically, it is thought that the first symptom is the classic “bulls-eye” rash, also called the erytherma migrans (EM).   The location of the rash is not restricted to the sight of the initial tick bite and may appear at multiple locations.  It is reported that anywhere between 50-60% of people do not notice a rash.[3]  The rash usually disappears without treatment in a month or so.

The rash may be accompanied by generalized fatigue, muscle or joint pain, stiffness, aches, swollen lymph nodes, headache, and occasionally a fever, resembling a flu or virus.  These symptoms as well, may disappear altogether and not reoccur for months or years. The disease progresses differently for each person so there is no typical path to follow in diagnoses.

Stage 2,  Early Disseminated Disease Lyme Disease,[4] can affect the central nervous system and heart (cardiac system). Early manifestations of lyme disease are sometimes unnoticed or disappear and disseminated (other organ systems involved) infection may occur weeks or months later.   Symptoms may include: blurred vision, fainting, general discomfort or uneasiness, headaches, heart palpitations, light headedness, joint inflammation in knees, hips, or other large joints, lethargy, fatigue, muscle pains, stiff or creaking neck.

Stage 3 or Late Stage or Chronic Lyme Disease[5] can occur weeks to years after the initial tick bite and may affect the skin, brain, nervous system, muscles, bones, and cartilage, including continuation or recurrence of the symptoms observed during Stages 1 and 2.

Lyme Disease symptoms are intermittent and changing, sometimes daily, with the exception of fatigue, which is often persistent and may be debilitating.[6]   Symptoms can be so variable that you may have days of near normality that alternate with days of profound debilitation.[7]  It is important to note that not everyone infected with Lyme Disease will develop noticeable symptoms.  Progression of Lyme Disease in some individuals is very gradual and often attributed to aging, busy lifestyle, etc.  Many individuals diagnosed, in hindsight, are able to identify emergence of symptoms that were previously dismissed.  

Although there are regional variations of Lyme Disease with general variations in symptoms (e.g. East coast lyme appears to have more severe neurological effects), the basic components of the disease are similar worldwide[8].   It appears that co-infections, which are very common in all lyme sufferers, exacerbate and prevent any remission of the disease.  The top 3 complaints from patients are usually pain, fatigue and cognitive problems. 

A more thorough list of symptoms that can occur with this disease is as follows:

 
 
 
 

Cognitive Symptoms

  • Brain fog
  • Concentration difficulties
  • Confusion
  • Declining school performance
  • Facial recognition difficulties
  • Memory impairment/word retrieval difficulties
  • Going to the wrong place
  • Slurred speech
  • Word reversals when speaking

Eyes/Vision

  • Vision loss
  • Choroiditis
  • Conjunctivitis
  • Drooping eyelid
  • Blurry vision
  • Double vision
  • Floaters
  • Foreign body sensation
  • Unexplained pain in eyes
  • Hypersensitivity to light
  • Scleritis (inflammation of the sclera, the white part of the eye)

Neurologic System

  • Clumsiness
  • Difficulties in coordination
  • Alzheimer like presentation
  • Demyelinating lesions or multiple sclerosis-like presentation
  • Dizziness
  • Encephalitis
  • Guillain-Barre’ syndrome  (immune system attacks parts of peripheral nervous system)
  • Hemiparesis  (muscle weakness on only one side of the body)
  • Numbness, tingling or burning
  • Parkinson-like presentation
  • Head pressure
  • Seizures
  • Forgetfulness
  • Poor short term memory
  • Word recall problems
  • Disorientation
  • Shooting or stabbing pains
  • Sleep disturbances
  • Hypersensitivity to smells
  • Hypersensitivity to tastes
  • Tremors/shaking
  • Vertigo
  • Walking difficulty
  • Poor balance

Gastrointestinal System

  • Abdominal pain or upset stomach
  • Abdominal distention
  • Anorexia
  • Constipation
  • Diarrhea
  • Kidney failure
  • Nausea
  • Urinary problems (irritable bladder, frequent urination)
  • Vomiting
  • Weight loss or gain

Psychological Symptoms

  • Anxiety and/or panic attacks
  • Behavioral changes
  • Depression
  • Overly emotional reactions
  • Hallucinations
  • Inappropriate laughter
  • Irritability
  • Mood changes
  • Nightmares
  • Paranoia
  • Rage or violent outbursts

Ears/Hearing

  • Hypersensitivity to sound
  • Hearing loss
  • Meniere’s disease (inner ear disorder causing  vertigo, tinnitus, fullness, or pressure)
  • Unexplained pain in ears
  • Ringing in the ears (tinnitus)

Skin/Hair

  • ACA (Acrodermatitis chronic atrophicans)
  • Anetoderma
  • Baker’s cyst
  • Fibrous nodules
  • Lymphocytoma
  • B-cell Lymphoma (skin cancer)
  • Petechia (small spots of bleeding under skin)
  • Rash (EM, Maculopapular, malar, hives)
  • Skin sclerosis – scleroderma
  • Unexplained hair loss

Head/Face/Neck

  • Bell’s Palsy
  • Unexplained facial or dental pain
  • Headaches
  • Hoarseness
  • Jaw pain, stiffness or TMJ
  • Facial twitching or muscle spasms
  • Neck pain, stiffness, pressure or creaking
  • Numbness or tingling of the face
  • Sore throat
  • Swallowing difficulty

Respiratory and Circulatory Systems

  • Chest pain
  • Cough
  • Carditis (inflammation of the pericardium, myocardium, or endocardium)
  • Shortness of breath

Musculoskeletal System

  • Backache, back pain
  • Bone pain, erosion, osteomyelitis (acute or chronic bone infection)
  • Carpal tunnel syndrome
  • Cartilage erosion
  • Cervical pain
  • Foot pain
  • Gout
  • Hand stiffness
  • Herniated disc
  • Joint pain
  • Joint swelling (arthritis)
  • Muscle pain (myalgia or fibromyalgia)
  • Tendonitis

General/Constitutional

  • Chills
  • Stiffness
  • Increased thirst

Reproduction Systems

  • Impotence
  • Testicular or pelvic pain/swelling
  • Unexplained milk production
  • Loss of libido/sexual disfunction
  • Unexplained breast pain

 

 


[1] Dr. Crist Website

[2] Benach JL; Coleman JL. Overview of spirochetal infections.  In Lyme Disease, ed. Coyle PK. St Louis: Mosby-YearBook, Inc.  pp. 61-68  1993

[3] Ilads website (What are the symptoms?)

[6] Clinical manifestations of Lyme Disease in the US, Trock, DH, Craft JE; Rahn DW, Connecticut Medicine, 53(6). 1989

[7] Pachner AR. Early dissmeninated Lyme disease.  American Journal of Medicine 1995,98 (suppl):4A-30S-43S.

[8] Steere AC. Lyme disease.  New England Journal of Medicine 1989;321:586-59

Disclaimer

The Midwest Lyme Foundation (MLF) and it's website is intended as a resource for people interested in learning about Lyme disease and other tick-borne illnesses. The information presented is for informational purposes only and is not intended as legal or medical advice regarding the treatment of any symptoms or disease. You should not use any information on the site to take the place of advice from your personal healthcare provider or other professional. Links to other sites are provided to facilitate research only and information on those sites is the opinion of those who publish the sites and is not necessarily that of Midwest Lyme Foundation.
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